Liquid metal polymer composite: Flexible, conductive, biocompatible, and antimicrobial scaffold
- 15 December 2021
- journal article
- research article
- Published by Wiley in Journal of Biomedical Materials Research Part B: Applied Biomaterials
- Vol. 110 (5), 1131-1139
- https://doi.org/10.1002/jbm.b.34987
Abstract
Gallium and its alloys, such as eutectic gallium indium alloy (EGaIn), a form of liquid metal, have recently attracted the attention of researchers due to their low toxicity and electrical and thermal conductivity for biomedical application. However, further research is required to harness EGaIn-composites advantages and address their application as a biomedical scaffold. In this research, EGaIn-polylactic acid/polycaprolactone composites with and without a second conductive filler, MXene, were prepared and characterized. The addition of MXene, into the EGaIn-composite, can improve the composite's electrochemical properties by connecting the liquid metal droplets resulting in electrically conductive continuous pathways within the polymeric matrix. The results showed that the composite with 50% EGaIn and 4% MXene, displayed optimal electrochemical properties and enhanced mechanical and radiopacity properties. Furthermore, the composite showed good biocompatibility, examined through interactions with fibroblast cells, and antibacterial properties against methicillin-resistant Staphylococcus aureus. Therefore, the liquid metal (EGaIn) polymer composite with MXene provides a first proof-of-concept engineering scaffold strategy with low toxicity, functional electrochemical properties, and promising antimicrobial properties.Keywords
This publication has 42 references indexed in Scilit:
- Transformable liquid-metal nanomedicineNature Communications, 2015
- Liquid-solid phase transition alloy as reversible and rapid molding bone cementBiomaterials, 2014
- Liquid Metal Angiography for Mega Contrast X-Ray Visualization of Vascular Network in Reconstructing In-Vitro Organ AnatomyIEEE Transactions on Biomedical Engineering, 2014
- Biomedical Implementation of Liquid Metal Ink as Drawable ECG Electrode and Skin CircuitPLOS ONE, 2013
- Two‐Dimensional Nanocrystals Produced by Exfoliation of Ti3AlC2Advanced Materials, 2011
- Tumor treating fields: concept, evidence and futureExpert Opinion on Investigational Drugs, 2011
- Harvesting human kinematical energy based on liquid metal magnetohydrodynamicsPhysics Letters A, 2009
- Eutectic Gallium‐Indium (EGaIn): A Liquid Metal Alloy for the Formation of Stable Structures in Microchannels at Room TemperatureAdvanced Functional Materials, 2008
- Software for quantification of labeled bacteria from digital microscope images by automated image analysisBioTechniques, 2005
- In vitro biocompatibility assessment of poly($epsiv;-caprolactone) films using L929 mouse fibroblastsBiomaterials, 2004