SMAC mimetics throw a molecular switch to control T H 17 responses
- 27 August 2019
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science Signaling
- Vol. 12 (596)
- https://doi.org/10.1126/scisignal.aay3986
Abstract
IL-17 produced by TH17 cells plays a central role in numerous protective and pathologic immune responses. In this issue of Science Signaling, Rizk et al. define a molecular switch controlled by the cellular inhibitor of apoptosis proteins that regulates TH17 immunity.Keywords
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