Cognitive process show how brain work from stimulus reception until stimuls reaction. With electroencephalogram (EEG) device, cognate process can be observerd in brain signal or EEG signal form. In cognitive process different kind of stimulus could affect generated brain signal. Also, given interference in cognitive prcess could affect brain signal. In this research, conducted observation whether gender difference has effect in cognitive process. Numerical stroop task with three kinds of conditions (congruence, incongruence, and neutral) are used as reference in signal observation process which is generated when the cognitive process in difference genders are done. The resulting EEG signal then conducted three kinds of analysis that is ERP analysis, reaction time, and energy analysis. The result of ERP analysis show both subject class have difference in response time that indicated with P3 peak time. On average, respons time in female (kongruent = 623,34 ms; inkongruent = 645,18 ms ; neutral = 614,91 ms)subject class is faster than male (kongruent = 709,67 ms; inkongruent = 745,00 ms; neutral =715,37 ms) subject class. Energy analysis show when numerical stroop task takes place, left side of the brain (51,36%) and cetral side of the brain (50,65%) more dominant than others parts of the brain.