Use of CytoSorb in the emergency department-high dependency unit: A case report and a mini review
Open Access
- 20 December 2021
- journal article
- review article
- Published by PAGEPress Publications in Emergency Care Journal
- Vol. 17 (4)
- https://doi.org/10.4081/ecj.2021.9825
Abstract
Circulating inflammatory mediators and cytokines play a pivotal role in the progression of sepsis, leading in turn to septic shock, organ failure and resistance to standard therapy. Blood purification therapies may be adjuvant treatment for severe sepsis, but results have been shown to be so far controversial. Recently, CytoSorb has achieved promising outcomes on reduction of cytokine blood levels, improvement of clinical parameters and mortality in sepsis, as well as in other acute conditions. It is mostly used in Intensive Care Unit (ICU), in isolated hemoperfusion, or inserted in other circuits in addition to Continuous Renal Replacement Therapy (CRRT), heart-lung machines and extracorporeal membrane oxygenation. We report a case of septic shock occurred in our Emergency Department-High Dependency Unit (ED-HDU), resistant to standard therapy and improved after CytoSorb, so avoiding ICU hospitalization.Keywords
This publication has 22 references indexed in Scilit:
- International registry on the use of the CytoSorb® adsorber in ICU patientsMedizinische Klinik - Intensivmedizin und Notfallmedizin, 2017
- Hemoadsorption by CytoSorb in septic patients: a case seriesCritical Care, 2017
- SOFA score in septic patients: incremental prognostic value over age, comorbidities, and parameters of sepsis severityInternal and Emergency Medicine, 2017
- Early report: The use of Cytosorb™ haemabsorption column as an adjunct in managing severe sepsis: initial experiences, review and recommendationsJournal of the Intensive Care Society, 2015
- Extracorporeal Renal Replacement Therapies in the Treatment of Sepsis: Where Are We?Seminars in Nephrology, 2015
- Hospital mortality of adults admitted to Intensive Care Units in hospitals with and without Intermediate Care Units: a multicentre European cohort studyCritical Care, 2014
- Septic Shock Secondary to β-hemolytic Streptococcus-induced Necrotizing Fasciitis treated with a Novel Cytokine Adsorption TherapyThe International Journal of Artificial Organs, 2014
- Hyperlactatemia and hypotension: looking at septic shock from different perspectivesEmergency Care Journal, 2013
- Critical care in the emergency departmentEuropean Journal of Emergency Medicine, 2009
- Potential Interventions in Sepsis-Related Acute Kidney InjuryClinical Journal of the American Society of Nephrology, 2008