Frequency and Factors Associated with Depression in Rheumatoid Arthritis in African Black Patients: Case-Control Study
Open Access
- 1 January 2019
- journal article
- research article
- Published by Scientific Research Publishing, Inc. in Open Journal of Rheumatology and Autoimmune Diseases
- Vol. 09 (02), 35-41
- https://doi.org/10.4236/ojra.2019.92004
Abstract
Objective: To study the frequency and factors associated with depression in rheumatoid arthritis (RA) among Black African patients. Patients and methods: It was a case-control study with a group of patients with RA (case) and a group of healthy subjects without rheumatoid arthritis (con-trols) matched by age and sex. All patients admitted to the rheumatologic department during February 2015 to July 2015 for rheumatoid arthritis meeting the criteria ACR/EULAR 2010, were included. Patients with high blood pressure, diabetes mellitus, renal failure or HIV infection have been excluded. Depression was assessed by the Hamilton Rating Scale for Depression. Results: Fifty patients with RA were included and compared to 100 healthy controls. For RA patients, it was 39 (78%) female and 11 (22%) male with a sex ratio of 0.28. In the control group, it was 77 (77%) female and 23 (23%) male with a sex ratio of 0.29. Twenty-seven (54%) patients with RA had depression compared with 17 (17%) subjects in the control group (p = 0.000). Impaired quality of life and a DAS 28 score greater than 3.2 were statistically associated with depression during RA with a p value respectively of 0.021 and 0.0000231. Conclusion: Depres-sion is significantly more common during RA than in non-RA controls. RA patients should be screened routinely for depression in order to ensure improved treatment and management.Keywords
This publication has 14 references indexed in Scilit:
- Anxiety and depression in rheumatoid arthritis: an epidemiologic survey and investigation of clinical correlates in Iranian populationRheumatology International, 2016
- Are depression and anxiety associated with disease activity in rheumatoid arthritis? A prospective studyBMC Musculoskeletal Disorders, 2016
- Increased risk of depression in patients with rheumatoid arthritis: a seven-year population-based cohort studyClinics, 2015
- Risk of Developing Depressive Disorders following Rheumatoid Arthritis: A Nationwide Population-Based StudyPLOS ONE, 2014
- Prévalence et facteurs prédictifs de la dépression au cours de la polyarthrite rhumatoïdeLa Presse Médicale, 2012
- The epidemiology of rheumatoid arthritis in Kinshasa, Democratic Republic of Congo--a population-based studyRheumatology, 2012
- Rheumatoid arthritis in Burkina Faso: clinical and serological profilesClinical Rheumatology, 2011
- Depression Is a Risk Factor for Noncompliance With Medical TreatmentArchives of Internal Medicine, 2000
- Development and validation of the european league against rheumatism response criteria for rheumatoid arthritis: Comparison with the preliminary american college of rheumatology and the world health organization/international league against rheumatism criteriaArthritis & Rheumatism, 1996
- A RATING SCALE FOR DEPRESSIONJournal of Neurology, Neurosurgery & Psychiatry, 1960