SD-OCT guided analysis of retinal nerve fibre layer in ammetropes in central India
Open Access
- 15 December 2022
- journal article
- Published by IP Innovative Publication Pvt Ltd in Indian Journal of Clinical and Experimental Ophthalmology
- Vol. 8 (4), 533-537
- https://doi.org/10.18231/j.ijceo.2022.108
Abstract
The retinal nerve fibre layer is a most crucial indicator of optic nerve damage in glaucoma as it advances visual field loss. Thickness of the RNFL can be measured using high resolution OCT. We conducted this study to evaluate the alterations in retinal nerve fibre layer thickness measured by SD- OCT in ametropes and to find various factors affecting RNFL thickness.: Study of retinal nerve fibre layer thickness (RNFL) by Optical Coherence Tomography (OCT) in ametropes in tertiary care hospital of central India.Hospital based prospective observational study included 300 eyes of 150 participants. Visiting ophthalmology outpatient department Gandhi medical college and fulfilling the inclusion and exclusion criteria.: Patients were divided into five groups of 60 eyes each on the basis of refractive status of eyes into emetropia, low hypermetropia, moderate hypermetropia, low mypopia and moderate mypopia. Subjects were subjected to OCT scan and RNFL thickness was measured. All groups were evaluated and observations were noted and results were analysed. To find the association between degree of ametropia and RNFL thickness one way ANOVA test was used. Correlation between axial length and RNFL was assesed by pearson correlation coefficient. p value <0.05 was considered as significant.: RNFL thickness in different groups followed ISNT rule with inferior quadrant showing the greatest thickness followed by the superior, nasal and temporal quadrants. The average RNFL thickness in emmetropics, Low hyperopic, Moderate hyperopic, Low myopic, Moderate myopic was 111.90μm, 110.58 μm, 114.59 μm, 103.33 μm, 93.33 μm respectively, wheras average axial length was 23.85mm, 22.36mm, 21.33mm, 24.72mm, 25.63mm.: With the help of OCT, we can differentiate the changes in RNFL thickness in various refractive errors. So, the refractive status of the eye should be kept in mind before making any ocular diagnosis in which the RNFL is a diagnostic criteria.Keywords
This publication has 12 references indexed in Scilit:
- Analysis of retinal nerve fiber layer thickness using optical coherence tomography in normal South Indian populationMuller Journal of Medical Sciences and Research, 2014
- Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCTOphthalmology, 2007
- Retinal Nerve Fiber Layer Measurements in Myopia: An Optical Coherence Tomography StudyInvestigative Ophthalmology & Visual Science, 2006
- Thickness Changes in the Fovea and Peripapillary Retinal Nerve Fiber Layer Depend on the Degree of MyopiaKorean Journal of Ophthalmology, 2006
- Estudio de parámetros de normalidad en relación a la edad con el Tomógrafo Óptico de CoherenciaArchivos de la Sociedad Española de Oftalmología, 2005
- Retinal thickness decreases with age: an OCT studyBritish Journal of Ophthalmology, 2003
- Thickness of the peripapillary retina in healthy subjects with different degrees of ametropiaOphthalmology, 2000
- Noninvasive mapping of the normal retinal thickness at the posterior poleOphthalmology, 1999
- Quantification of Nerve Fiber Layer Thickness in Normal and Glaucomatous Eyes Using Optical Coherence TomographyAmerican Journal of Ophthalmology, 1995
- Chronic Human Glaucoma Causing Selectively Greater Loss of Large Optic Nerve FibersOphthalmology, 1988