Probiotics and postbiotics play a role in maintaining dermal health
- 14 March 2023
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Food & Function
- Vol. 14 (9), 3966-3981
- https://doi.org/10.1039/d3fo00152k
Abstract
Probiotics and postbiotics have emerged as an alternative to traditional antibiotics for the treatment of persistent skin infections. The use of probiotics and postbiotics has been shown to have a positive impact on the maintenance of skin health by promoting the growth of beneficial bacteria and inhibiting the growth of harmful bacteria. Probiotics work by adhering to the skin and mucosal membranes and competing with pathogenic organisms for nutrients, which prevent the growth of harmful bacteria. In addition, probiotics and postbiotics produce antimicrobial substances that help eliminate pathogenic bacteria, resulting in improved skin health. The skin is the largest organ in the body and serves as a protective barrier against external pathogens. When harmful bacteria colonize the skin, it can lead to tissue damage and disruption, which can cause chronic inflammatory, non-healing skin disorders such as dermatitis, psoriasis, and acne. Traditional treatments for persistent skin infections rely heavily on antibiotics, which can have several adverse effects on the body, including the development of antibiotic resistance. Moreover, pathogens such as Pseudomonas aeruginosa and Staphylococcus aureus, which are often implicated in chronic skin infections, can form biofilms that are highly resistant to antibiotics and host immune responses. In recent years, research has shown that probiotics and postbiotics can play a significant role in the maintenance of dermal health. Probiotics and postbiotics can stimulate the immune system, enhance the production of skin barrier components, and modulate skin inflammation, all of which are critical for the maintenance of healthy skin. In this review, we have compiled the current literature on the therapeutic potential of probiotics and postbiotics for the treatment of persistent skin infections and their impact on maintaining dermal health.This publication has 109 references indexed in Scilit:
- Bifidobacterium infantis35624 modulates host inflammatory processes beyond the gutGut Microbes, 2013
- Lactobacillus reuteri Protects Epidermal Keratinocytes from Staphylococcus aureus-Induced Cell Death by Competitive ExclusionApplied and Environmental Microbiology, 2012
- Probiotic Interference ofLactobacillus rhamnosusGR-1 andLactobacillus reuteriRC-14 with the Opportunistic Fungal PathogenCandida albicansInfectious Diseases in Obstetrics and Gynecology, 2012
- Randomised clinical trial: the effectiveness of Lactobacillus reuteri ATCC 55730 rectal enema in children with active distal ulcerative colitisAlimentary Pharmacology & Therapeutics, 2011
- Peptidoglycan from lactobacilli inhibits interleukin‐12 production by macrophages induced by Lactobacillus casei through Toll‐like receptor 2‐dependent and independent mechanismsImmunology, 2009
- Oral Probiotic Control Skin Inflammation by Acting on Both Effector and Regulatory T CellsPLOS ONE, 2009
- Staphylococcus aureus Infection of Epidermal Keratinocytes Promotes Expression of Innate Antimicrobial PeptidesInfection and Immunity, 2005
- Bacterial products increase expression of the human cathelicidin hCAP-18/LL-37 in cultured human sinus epithelial cellsFEMS Immunology & Medical Microbiology, 2004
- Lactobacilluscasei reduces CD8+ T cell‐mediated skin inflammationEuropean Journal of Immunology, 2004
- Changes in some components of soymilk during fermentation with bifidobacteriaFood Research International, 2000