Abstract
Background: Shivering is a common problem during the perioperative period, in surgeries done under regional anesthesia. Shivering is a potentially serious complication, resulting in increased metabolic rate; increased oxygen consumption along with raised carbon dioxide production; ventilation and cardiac output; adverse postoperative outcomes, such as wound infection; increased surgical bleeding; and morbid cardiac events.4,5 Present study aimed to compare the efficacy of butorphanol versus clonidine for control of shivering in patients undergoing surgeries under spinal anaesthesia. Material and Methods: Present study was conducted patients aged between 18-60 years, of either sex, ASA physical status I/II, scheduled for elective lower abdominal surgeries under subarachnoid block. 60 Patients were randomly allocated using a computer generated table of random numbers. Group B (n= 30) received intravenous bolus butorphanol 1 mg while group C (n= 30) received an intravenous bolus of 150 μg (1 mL) clonidine. Results: In present study, 60 patients were randomly allocated into group B (n= 30, received butorphanol) and group C (n= 30, received clonidine). Age (years), weight (Kg), BMI(Kg/m2), Gender (Male/Female), ASA grade, duration of surgery (min) and baseline axillary temperature were comparable between both groups and no statistically significant difference was noted among them. In butorphanol group an earlier onset of sensory as well as motor block and prolonged duration of sensory as well as motor block was noted as compared to clonidine group and difference was statistically significant. In present study, higher incidence of shivering was noted in clonidine group as compared to butorphanol group and difference was statistically significant. Side effects, such as hypotension, nausea and vomiting werer more in clonidine group as compared to butorphanol group and difference was statistically significant. Bradycardia was noted in both groups in 3 patients. Conclusion: Intravenous butorphanol is a safe and effective for prevention of shivering as well as had early onset and prolonged duration of sensory/motor block.