Cardiac biomarkers and detection methods for myocardial infarction
- 10 September 2022
- journal article
- review article
- Published by Springer Science and Business Media LLC in Molecular & Cellular Toxicology
- Vol. 18 (4), 443-455
- https://doi.org/10.1007/s13273-022-00287-1
Abstract
Background A significant heart attack known as a myocardial infarction (MI) occurs when the blood supply to the heart is suddenly interrupted, harming the heart muscles due to a lack of oxygen. The incidence of myocardial infarction is increasing worldwide. A relationship between COVID-19 and myocardial infarction due to the recent COVID-19 pandemic has also been revealed. Objective We propose a biomarker and a method that can be used for the diagnosis of myocardial infarction, and an aptamer-based approach. Results For the diagnosis of myocardial infarction, an algorithm-based diagnosis method was developed using electrocardiogram data. A diagnosis method through biomarker detection was then developed. Conclusion Myocardial infarction is a disease that is difficult to diagnose based on the aspect of a single factor. For this reason, it is necessary to use a combination of various methods to diagnose myocardial infarction quickly and accurately. In addition, new materials such as aptamers must be grafted and integrated into new ways. Purpose of Review The incidence of myocardial infarction is increasing worldwide, and some studies are being conducted on the association between COVID-19 and myocardial infarction. The key to properly treating myocardial infarction is early detection, thus we aim to do this by offering both tools and techniques as well as the most recent diagnostic techniques. Recent Findings Myocardial infarction is diagnosed using an electrocardiogram and echocardiogram, which utilize cardiac signals. It is required to identify biomarkers of myocardial infarction and use biomarker-based ELISA, SPR, gold nanoparticle, and aptamer technologies in order to correctly diagnose myocardial infarction.Keywords
Funding Information
- NRF (No.2021R1F1A1063744)
This publication has 137 references indexed in Scilit:
- An In Silico Analysis of Troponin I Mutations in Hypertrophic Cardiomyopathy of Indian OriginPLOS ONE, 2013
- Lipid Profile of Patients with Acute Myocardial Infarction and its Correlation with Systemic InflammationBiomarker Insights, 2013
- The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency departmentBMC Medicine, 2012
- Clinical application of stem cell therapy in Parkinson's diseaseBMC Medicine, 2012
- Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhageCritical Care, 2011
- Prognostic value of echocardiography after acute myocardial infarctionHeart, 2009
- Signs and symptoms in diagnosing acute myocardial infarction and acute coronary syndrome: a diagnostic meta-analysisBritish Journal of General Practice, 2008
- Release of fatty acid-binding protein from isolated rat heart subjected to ischemia and reperfusion or to the calcium paradoxBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988
- Value of early two dimensional echocardiography in patients with acute myocardial infarctionThe American Journal of Cardiology, 1982
- Echocardiography in acute myocardial infarctionThe American Journal of Cardiology, 1975