Modelling speech motor programming and apraxia of speech in the DIVA/GODIVA neurocomputational framework
- 18 May 2020
- journal article
- research article
- Published by Taylor & Francis Ltd in Aphasiology
- Vol. 35 (4), 424-441
- https://doi.org/10.1080/02687038.2020.1765307
Abstract
Background: The Directions Into Velocities of Articulators (DIVA) model and its partner, the Gradient Order DIVA (GODIVA) model, provide neurobiologically grounded, computational accounts of speech motor control and motor sequencing, with applications for the study and treatment of neurological motor speech disorders. Aims: In this review, we provide an overview of the DIVA and GODIVA models and how they explain the interface between phonological and motor planning systems to build on previous models and provide a mechanistic accounting of apraxia of speech (AOS), a disorder of speech motor programming. Main Contribution: Combined, the DIVA and GODIVA models account for both the segmental and suprasegmental features that define AOS via damage to (i) a speech sound map, hypothesized to reside in the left ventral premotor cortex, (ii) a phonological content buffer hypothesized to reside in the left posterior inferior frontal sulcus, and/or (iii) the axonal projections between these regions. This account is in line with a large body of behavioural work, and it unifies several prior theoretical accounts of AOS. Conclusions: The DIVA and GODIVA models provide an integrated framework for the generation and testing of both behavioural and neuroimaging hypotheses about the underlying neural mechanisms responsible for motor programming in typical speakers and in speakers with AOS.Keywords
Funding Information
- National Institutes of Health (R01 DC007683, R01 DC002852, T32 DC013017)
This publication has 68 references indexed in Scilit:
- Disrupted functional connectivity in primary progressive apraxia of speechNeuroImage: Clinical, 2018
- Behavioral and neurobiological correlates of childhood apraxia of speech in Italian childrenBrain and Language, 2015
- The role of candidate-geneCNTNAP2in childhood apraxia of speech and specific language impairmentNeuropsychiatric Genetics, Part B of the American Journal of Medical Genetics (AJMG), 2015
- Patterns of Poststroke Brain Damage That Predict Speech Production Errors in Apraxia of Speech and Aphasia DissociateStroke, 2015
- Computational modeling of stuttering caused by impairments in a basal ganglia thalamo-cortical circuit involved in syllable selection and initiationBrain and Language, 2013
- Neural Representations and Mechanisms for the Performance of Simple Speech SequencesJournal of Cognitive Neuroscience, 2010
- An fMRI investigation of syllable sequence productionNeuroImage, 2006
- The role of dominant premotor cortex in language: a study using intraoperative functional mapping in awake patientsNeuroImage, 2003
- Syllable frequency and syllable structure in apraxia of speechBrain and Language, 2003
- Speech motor programming in apraxia of speechJournal of Phonetics, 2002