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Human epidermal growth factor receptor 2 amplification detection by droplet digital polymerase chain reaction in formalin-fixed paraffin-embedded breast and gastric cancer samples

Hong Feng, Xingwen Wang, Yunyan Wu, Xueling Song, Chengtao Sun, Changshun Wu
Published: 1 January 2017
 by  Medknow

Abstract: DdPCR was able to identify HER2 amplification status in breast and gastric cancers with precise correlation with IHC and FISH results. This method might become a standard method for testing FFPE samples. However, the technology requires further research.
Keywords: droplet / paraffin / formalin / IHC / epidermal / FISH / HER2 / FFPE / digital / precise

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