NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines
Open Access
- 31 December 2020
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 11 (4), 276-279
- https://doi.org/10.5155/eurjchem.11.4.276-279.2009
Abstract
A simple and eloquent procedure for the synthesis of a new series of thienyl benzo[b]1,4-diazepines is reported. They were synthesized by the condensation of o-phenylenediamine (o-PDA) with distinct hetero chalcones using NaOH in polyethylene glycol (PEG-400) as green and alternative reaction solvent. The significances of this present method are shorter reaction time, easy work-up, high yields, and mild reaction conditions. Furthermore, this method is environment friendly and without use of an expensive catalyst. The all newly synthesized compounds are characterized by the spectroscopic methods.Keywords
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