Wet Electrospinning and its Applications: A Review
Open Access
- 16 June 2022
- journal article
- review article
- Published by Instituto Tecnologico Metropolitano (ITM) in TecnoLógicas
- Vol. 25 (54), e2223
- https://doi.org/10.22430/22565337.2223
Abstract
In wet electrospinning, a natural or synthetic polymer solution is deposited on a non-solvent liquid coagulant used as collector. This technique can create 3D nanofiber scaffolds with better properties (e.g., porosity and high surface area) than those of traditional 2D scaffolds produced by standard electrospinning. Thanks to these characteristics, wet electrospinning can be employed in a wide range of tissue engineering and industrial applications. This review aims to broaden the panorama of this technique, its possible fields of action, and its range of common materials. Moreover, we also discuss its future trends. In this study, we review papers on this method published between 2017 and 2021 to establish the state of the art of wet electrospinning and its most important applications in cardiac, cartilage, hepatic, wound dressing, skin, neural, bone, and skeletal muscle tissue engineering. Additionally, we examine its industrial applications in water purification, air filters, energy, biomedical sensors, and textiles. The main results of this review indicate that 3D scaffolds for tissue engineering applications are biocompatible; mimic the extracellular matrix (ECM); allow stem cell viability and differentiation; and have high porosity, which provides greater cell infiltration compared to 2D scaffolds. Finally, we found that, in industrial applications of wet electrospinning: (1) additives improve the performance of pure polymers; (2) the concentration of the solution influences porosity and fiber packing; (3) flow rate, voltage, and distance modify fiber morphology; (4) the surface tension of the non-solvent coagulant on which the fibers are deposited has an effect on their porosity, compaction, and mechanical properties; and (5) deposition time defines scaffold thickness.Keywords
This publication has 74 references indexed in Scilit:
- Nanofiber Yarn/Hydrogel Core–Shell Scaffolds Mimicking Native Skeletal Muscle Tissue for Guiding 3D Myoblast Alignment, Elongation, and DifferentiationACS Nano, 2015
- Electrospinning of Nanofibers and Their Applications for Energy DevicesJournal of Nanomaterials, 2015
- Affecting parameters on electrospinning process and characterization of electrospun gelatin nanofibersFood Hydrocolloids, 2014
- Electrospinning for regenerative medicine: a review of the main topicsDrug Discovery Today, 2014
- Advances in three-dimensional nanofibrous macrostructures via electrospinningProgress in Polymer Science, 2013
- Nanotechnology – a new route to high-performance functional textilesTextile Progress, 2011
- Electrospinning: A fascinating fiber fabrication techniqueBiotechnology Advances, 2010
- Morphological and mechanical characteristics of the reconstructed rat abdominal wall following use of a wet electrospun biodegradable polyurethane elastomer scaffoldBiomaterials, 2010
- Electrospun nanofibers in energy and environmental applicationsEnergy & Environmental Science, 2008
- Poly(m‐Phenylene Isophthalamide) Ultrafine Fibers from an Ionic Liquid Solution by Dry‐Jet‐Wet‐ElectrospinningJournal of Macromolecular Science, Part B, 2006