Background: Breast cancer is the most frequent malignancy in women worldwide .in Iraq Breast cancer ranks first among cancer diagnosed in women, the goal of this study is to bring the lights towards the importance of most common risk factors to reduce the incidence of breast cancer. Materials and methods: A case control study of breast cancer women who attended oncology unit and Baghdad educational hospital in Baghdad between first of June 2018, and first of September 2018, the cases were (60) and control (90) all of them use formula that contain (marital status of women, age, occupation, parity, age of first child, age of menarche, of menopause, smoking, use of contraceptive pills, body mass index, family history of breast cancer) and cases was all had medical records available. We use SPSS version 23. Each parameter is compared separately for statistically significant differences. Results: In this study show that the mean age of cases (48.30) and the mean of control (34.42) . And as we show the domiation from house wife with percentage (71%) regarding case but the control also show like this percentage. The BMI show so close mean between case (28.1) and control (27.07) and has no effect on disesas , the martial status was 84.7% of both cases and control so no statisticaly significant, the gravity, abortion and breast feeding show no significant differences. The family history shows highly significant, in case show (24) person from (60) have family member with diseas, most of them have (sister) with BC . Radiation and smoking show no statistically differences, regarding radiation only 14 women of all sample had exposure to radiation from different source. The contraceptive show significant differences there is (35) of case from (60) use contraceptive drug they have breast cancer. Conclusion: The majority of women with breast cancer were had been in the 5th decade and we show in this study no relation between smoking and BC, women with family history has more risk to have BC. Contraceptive pills is also strong predictor of Breast cancer.