Premenstrual syndrome, a common but underrated entity: review of the clinical literature
Open Access
- 28 May 2021
- journal article
- review article
- Published by Galenos Yayinevi in Journal of the Turkish-German Gynecological Association
- Vol. 22 (2), 139-148
- https://doi.org/10.4274/jtgga.galenos.2021.2020.0133
Abstract
Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) are characterized by somatic and psychologic symptoms that arise at the luteal phase of the menstrual cycle and subside with menstruation. For definitive diagnosis prospectively self-reported symptoms should demonstrate a cyclic pattern and other psychological pathologies and thyroid dysfunction, that may present with similar symptoms, should be excluded. Both entities affect millions of women at reproductive age as the prevalence of PMS is given as 10-98% while PMDD affects 2-8%. Sex steroids and neurotransmitters have a central role in the etiology. The role of vitamins and minerals in the etiology and treatment of PMS and PMDD is open to discussion. Drugs that suppress ovarian sex steroid production, such as combined oral contraceptives or selective scrotonin reuptake inhibitors enhancing central serotonin delivery are used for treatment. Life-style changes and regular exercise also have a positive effect in milder cases. Tricyclic antidepressants and gonadotropin-releasing hormone analogues can be used in selected cases.Keywords
This publication has 74 references indexed in Scilit:
- Criteria for Premenstrual Dysphoric DisorderArchives of General Psychiatry, 2012
- Global study of women's experiences of premenstrual symptoms and their effects on daily lifeMenopause International, 2011
- Estrogen receptor alpha (ESR-1) associations with psychological traits in women with PMDD and controlsJournal of Psychiatric Research, 2010
- Selective Serotonin Reuptake Inhibitors for Premenstrual Syndrome and Premenstrual Dysphoric DisorderObstetrics & Gynecology, 2008
- Premenstrual syndromeThe Lancet, 2008
- The prevalence of premenstrual dysphoric disorder in a randomly selected group of urban and rural womenPsychological Medicine, 2008
- Risk for Premenstrual Dysphoric Disorder Is Associated with Genetic Variation in ESR1, the Estrogen Receptor Alpha GeneBiological Psychiatry, 2007
- Plasma copper, zinc and magnesium levels in patients with premenstrual tension syndromeActa Obstetricia et Gynecologica Scandinavica, 1994
- Vitamin B6 in the treatment of the premenstrual syndrome–reviewBJOG: An International Journal of Obstetrics and Gynaecology, 1991
- Plasma progesterone, oestradiol 17 β and premenstrual symptomsActa Psychiatrica Scandinavica, 1979