Bioorthogonally Assisted Phototherapy: Recent Advances and Prospects
Open Access
- 24 May 2023
- journal article
- review article
- Published by Wiley in Angewandte Chemie
- Vol. 62 (33), e202303198
- https://doi.org/10.1002/anie.202303198
Abstract
Photoresponsive materials offer excellent spatiotemporal control over biological processes and the emerging phototherapeutic methods are expected to have significant effects on targeted cancer therapies. Recent examples show that combination of photoactivatable approaches with bioorthogonal chemistry enhances the precision of targeted phototherapies and profound implications are foreseen particularly in the treatment of disperse/diffuse tumors. The extra level of on-target selectivity and improved spatial/temporal control considerably intensified related bioorthogonally assisted phototherapy research. The anticipated growth of further developments in the field justifies the timeliness of a brief summary of the state of the art.Funding Information
- Nemzeti Kutatási Fejlesztési és Innovációs Hivatal (NKFIH-K-143581, NKFIH-PD-135121 and VEKOP-2.3.3-15-2016-00011)
- Magyar Tudományos Akadémia Számítástechnikai és Automatizálási Kutatóintézet (BO/00204/21)
- Magyar Tudományos Akadémia (140/3/2023/KP)
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