Social and political instability threatens the economic and social development of nations. Political persecution is therefore characterized by socio-political instability as a barrier to development that creates economic difficulties, limited public and private investments and hinders national development. This article describes political persecution and economic development through a close examination of the African ministry which covers key issues such as welfare and drug trafficking. We use various measures to measure political violence and economic development, and we use the crisis management strategies of Driscoll and Kraay and a comprehensive time-based approach to measure (GMM) for a sample of Sub Saharan African countries in the period 2000-2014. In the example of political persecution, we find that the combination of individual achievement, education, capture, and health has a negative impact on politics, but GINI, unemployment, drugs and homeless people that have a positive impact on violence. In the example of the economy, political violence, armed with bribery and corruption, has a negative impact on economic development, but population, security, employment, political participation, housing have a negative impact on production and on economic progress. Positive impact on economic development. The findings underscore the importance of implementing social policies and guidelines against political violence to increase economic growth and development, productivity, political participation and human security in the regions of Africa.