Palisaded encapsulated neuroma on the lower lip: a case report
Open Access
- 30 April 2022
- journal article
- research article
- Published by Yeungnam University College of Medicine in Journal of Yeungnam Medical Science
- Vol. 39 (2), 168-171
- https://doi.org/10.12701/yujm.2021.01088
Abstract
Palisading encapsulated neuroma is a rare, benign, cutaneous nerve sheath tumor. It usually occurs as an asymptomatic solitary skin-colored papule and commonly affects the nose and cheeks. Sometimes, it involves other sites, including the shoulder, upper arm, and trunk, but rarely involves the oral mucosa, including that of the lip. In our case, a 63-year-old female patient complained of a pinkish rubbery nodule on her lower lip. Histopathologic examination demonstrated a well-circumscribed nodule encapsulated by connective tissue stroma in the dermis. The nodule consisted of palisading spindle-shaped tumor cells with wavy and basophilic nu-clei. The cells were arranged in streaming fascicles with multiple clefts and were strongly positive for S-100 proteins. To our knowl-edge, only three cases of palisading encapsulated neuroma on the lower lip have been reported in the Korean literature. Herein, we re-port a rare case of an oral palisaded encapsulated neuroma.Keywords
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