Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway
Open Access
- 2 January 2014
- journal article
- research article
- Published by Springer Science and Business Media LLC in British Journal of Cancer
- Vol. 110 (4), 946-957
- https://doi.org/10.1038/bjc.2013.789
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Comprehensive molecular characterization of human colon and rectal cancerNature, 2012
- Smad4-Mediated Signaling Inhibits Intestinal Neoplasia by Inhibiting Expression of β-CateninGastroenterology, 2012
- Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cellsOncogene, 2010
- Antimetastatic Role of Smad4 Signaling in Colorectal CancerGastroenterology, 2010
- Targeting transforming growth factor-β signaling in liver metastasis of colon cancerCancer Letters, 2009
- Activation of Wnt/β-catenin signalling pathway induces chemoresistance to interferon-α/5-fluorouracil combination therapy for hepatocellular carcinomaBritish Journal of Cancer, 2009
- TGFβ in CancerCell, 2008
- In vitro and in vivo reversal of resistance to 5-fluorouracil in colorectal cancer cells with a novel stealth double-liposomal formulationBritish Journal of Cancer, 2007
- Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancerNature Reviews Drug Discovery, 2004
- Smad-dependent and Smad-independent pathways in TGF-β family signallingNature, 2003