Data mining techniques are used to extract interesting patterns and discover meaningful knowledge from huge amount of data. There has been increasing in usage of data mining techniques on medical data for determining useful trends and patterns that are used in analysis and decision making. About eighty percent of human deaths occurred in low and middle-income countries due to heart diseases. The healthcare industry generates large amount of heart disease data which are not organized. These data make the prediction process more complicated and voluminous. Data mining provides the techniques for fast and accurate transformation of data into useful information for heart diseases prediction. The main objectives of this research is to predict heart diseases more accurately using Naïve Bayes, J48 Decision Tree, Neural Network, Random Forest classification algorithms and compare the performance of classifiers. The research uses raw dataset for performance analysis and the analysis is based on Weka Tool. This research also shows best technique from them which is Random Forest on the basis of accuracy and execution time.