Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3
Open Access
- 15 May 2020
- journal article
- research article
- Published by American Association for Cancer Research (AACR) in Cancer Research
- Vol. 80 (10), 1957-1969
- https://doi.org/10.1158/0008-5472.can-19-0334
Abstract
This study shows that EBV-encoded BART2-5p miRNA suppresses expression of the RND3 Rho family GTPase, consequently promoting ROCK signaling, cell motility, and metastatic behavior of NPC cells.Other Versions
Funding Information
- Hong Kong Research Grant Council (AoE/M-06/08)
- General Research Fund (GRF17161116, C7027-16G)
- National Key R&D Program of China (2017YFC1309000)
- Shenzhen Peacock Team Project (KQTD201533117210153, KQTD2018041118502879)
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