Enhancing COVID-19 Epidemic Forecasting Accuracy by Combining Real-time and Historical Data From Multiple Internet-Based Sources: Analysis of Social Media Data, Online News Articles, and Search Queries

Abstract
Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: The SARS-COV-2 virus and its variants are posing extraordinary challenges for public health worldwide. More timely and accurate forecasting of COVID-19 epidemics is the key to maintaining timely interventions and policies and efficient resources allocation. Internet-based data sources have shown great potential to supplement traditional infectious disease surveillance, and the combination of different Internet-based data sources has shown greater power to enhance epidemic forecasting accuracy than using a single Internet-based data source. However, existing methods incorporating multiple Internet-based data sources only used real-time data from these sources as exogenous inputs, but didn’t take all the historical data into account. Moreover, the predictive power of different Internet-based data sources in providing early warning for COVID-19 outbreaks has not been fully explored. Objective: The main aim of our study is to explore whether combining real-time and historical data from multiple Internet-based sources could improve the COVID-19 forecasting accuracy over the existing baseline models. A secondary aim is to explore the COVID-19 forecasting timeliness based on different Internet-based data sources. Methods: We first used core terms and symptoms related keywords-based methods to extract COVID-19 related Internet-based data from December 21, 2019, to February 29, 2020. The Internet-based data we explored included 90,493,912 online news articles, 37,401,900 microblogs, and all the Baidu search query data during that period. We then proposed an autoregressive model with exogenous inputs, incorporating the real-time and historical data from multiple Internet-based sources. Our proposed model was compared with baseline models, and all the models were tested during the first wave of COVID-19 epidemics in Hubei province and the rest of mainland China separately. We also used the lagged Pearson correlations for the COVID-19 forecasting timeliness analysis. Results: Our proposed model achieved the highest accuracy in all the five accuracy measures, compared with all the baseline models in both Hubei province and the rest of mainland China. In mainland China except Hubei, the COVID-19 epidemics forecasting accuracy differences between our proposed model (model i) and all the other baseline models were statistically significant (model 1, t=–8.722, P<.001; model 2, t=–5.000, P<.001, model 3, t=–1.882, P =0.063, model 4, t=–4.644, P<.001; model 5, t=–4.488, P<.001). In Hubei province, our proposed model's forecasting accuracy improved significantly compared with the baseline model using historical COVID-19 new confirmed case counts only (model 1, t=–1.732, P=0.086). Our results also showed that Internet-based sources could provide a 2-6 days earlier warning for COVID-19 outbreaks. Conclusions: Our approach incorporating real-time and historical data from multiple Internet-based sources could improve forecasting accuracy for COVID-19 epidemics and its variants, which may help improve public health agencies' interventions and resources allocation in mitigating and controlling new waves of COVID-19 or other epidemics.

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