Abstract
Acute Acalculous Cholecystitis “AAC” is defined by inflammation of the gallbladder without the presence of gallstones. It is by far less common than acute calculous cholecystitis where it only counts 5-10% of all cases of acute cholecystitis. In a patient with the disease of systemic lupus erythematous (SLE) having a gallbladder disorder is not common. Herein, we present a 43-year- old lady who is known case of hypertension, SLE, and End-stage renal disease on hemodialysis due to lupus nephritis presented to the emergency department with a right upper abdominal pain, and abdominal ultrasound revealed acalcular cholecystitis. Further diagnostic tools supported the diagnosis, and she underwent after preparation uneventful laparoscopic cholecystectomy (LC).