Motor Learning Promotes the Coupling between Fast Spindles and Slow Oscillations Locally over the Contralateral Motor Network
- 14 October 2021
- journal article
- research article
- Published by Oxford University Press (OUP) in Cerebral Cortex
- Vol. 32 (12), 2493-2507
- https://doi.org/10.1093/cercor/bhab360
Abstract
Recent studies from us and others suggest that traditionally declarative structures mediate some aspects of the encoding and consolidation of procedural memories. This evidence points to the existence of converging physiological pathways across memory systems. Here, we examined whether the coupling between slow oscillations (SO) and spindles, a mechanism well established in the consolidation of declarative memories, is relevant for the stabilization of human motor memories. To this aim, we conducted an electroencephalography study in which we quantified various parameters of these oscillations during a night of sleep that took place immediately after learning a visuomotor adaptation (VMA) task. We found that VMA increased the overall density of fast (≥12 Hz), but not slow (<12 Hz), spindles during nonrapid eye movement sleep, stage 3 (NREM3). This modulation occurred rather locally over the hemisphere contralateral to the trained hand. Although adaptation learning did not affect the density of SOs, it substantially enhanced the number of fast spindles locked to the active phase of SOs. The fact that only coupled spindles predicted overnight memory retention points to the relevance of this association in motor memory consolidation. Our work provides evidence in favor of a common mechanism at the basis of the stabilization of declarative and motor memories.Funding Information
- Tokyo Ohka Foundation for The Promotion of Science and Technology (PICT2018-1150, PICT2015-0844)
- Ministry of Defence (PIDDEF-2014-2017#17)
This publication has 91 references indexed in Scilit:
- Daytime Sleep Enhances Consolidation of the Spatial but Not Motoric Representation of Motor Sequence MemoryPLOS ONE, 2013
- Sleep spindles are locally modulated by training on a brain–computer interfaceProceedings of the National Academy of Sciences of the United States of America, 2012
- Fast and Slow Spindles during the Sleep Slow Oscillation: Disparate Coalescence and Engagement in Memory ProcessingSleep, 2011
- Measuring Phase-Amplitude Coupling Between Neuronal Oscillations of Different FrequenciesJournal of Neurophysiology, 2010
- Contribution of night and day sleep vs. simple passage of time to the consolidation of motor sequence and visuomotor adaptation learningExperimental Brain Research, 2009
- Reconsidering the role of sleep for motor memory.Behavioral Neuroscience, 2009
- Consolidation Patterns of Human Motor MemoryJournal of Neuroscience, 2008
- Daytime Naps, Motor Memory Consolidation and Regionally Specific Sleep SpindlesPLOS ONE, 2007
- Odor Cues During Slow-Wave Sleep Prompt Declarative Memory ConsolidationScience, 2007
- Patterns of Interference in Sequence Learning and Prism Adaptation Inconsistent With the Consolidation HypothesisLearning & Memory, 2002