Prognostic value of lncRNA ROR expression in various cancers: a meta-analysis
Open Access
- 28 September 2018
- journal article
- research article
- Published by Portland Press Ltd. in Bioscience Reports
- Vol. 38 (5)
- https://doi.org/10.1042/bsr20181095
Abstract
Background: There is a dispute on the prognostic value of long non-coding RNA regulator of reprogramming (lncRNA ROR) in cancers. The purpose of this study was to evaluate the prognostic significance of lncRNA ROR expression in human cancers. Methods: PubMed, Embase and Cochrane Library were searched to look for relevant studies. The meta-analyses of prognostic and clinicopathological parameters were conducted. Results: A total of 10 studies were finally included into the meta-analysis. High lncRNA ROR expression was significantly associated with shorter overall survival (OS) (HR=2.88, 95%CI=2.16-3.84, P Conclusion: High lncRNA ROR expression was associated with worse prognosis in cancers. LncRNA ROR expression could serve as an unfavorable prognostic factor in various cancers.This publication has 37 references indexed in Scilit:
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