Efficacy of ozonized sunflower oil as treatment of canine generalized demodicosis
Open Access
- 18 March 2021
- journal article
- Published by Heighten Science Publications Corporation in Insights in Veterinary Science
- Vol. 5 (1), 015-021
- https://doi.org/10.29328/journal.ivs.1001030
Abstract
Background: The acaricidal action of Ozonized sunflower oil (OSO) has demonstrated in different clinical cases of different animal species, such as psoroptic rabbits and pig sarcoptic scabies and recently in demodesic goat. Objectives: This study evaluated the effectiveness of OSO as treatment for generalized demodicosis mange in dogs. Animals: Twenty dogs of different breeds, between six months and one year of age with generalized demodicosic mange that attended to Veterinary Clinic “José Luis Callejas” Havana, Cuba, during the year 2015, were included in the study. Methods: The demodicosis diagnostic was based on its clinical history, the mite’s presence by deep scraping and clinical signs. All cases had a history of receiving before conventional treatments without solution. OSO treatment was topically applied daily, every 12 hours, after shaving all affected areas. Monitoring of clinical signs, mite counting on scaling, pruritus and capillary regrowth (7, 14, 28, 56 and 84 days) were performed. Results: The results showed a significant reduction of mite counts, clinical signs and pruritus since the 7th day of application. The animals recovered the fur on more than 90% of the body surface. All the animals (100%) recovered from generalized demodesic mange in 84 days of treatment. Conclusion: The effectiveness and safety of OSO as election treatment of generalized demodicosis mange in dogs was demonstrated.Keywords
This publication has 29 references indexed in Scilit:
- Efficacy of a topical application of Certifect®(fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) for the treatment of canine generalized demodicosisParasite, 2013
- Treatment of canine generalized demodicosis associated with hyperadrenocorticism with spot-on moxidectin and imidaclopridActa Veterinaria Scandinavica, 2013
- The role of apoptosis in immunosuppression of dogs with demodicosisVeterinary Immunology and Immunopathology, 2011
- Antioxidant effect of an ozonized theobroma oil formulation on damaged-inflammatory rat skinGrasas y Aceites, 2011
- Synergy between fipronil and amitraz in a Rhipicephalus sanguineus tick residual contact testExperimental and Applied Acarology, 2011
- Treatment of canine‐generalized demodicosis: a blind, randomized clinical trial comparing the efficacy of Advocate®(Bayer Animal Health) with ivermectinVeterinary Dermatology, 2009
- Treatment of canine generalized demodicosis with a ‘spot‐on’ formulation containing 10% moxidectin and 2.5% imidacloprid (Advocate®, Bayer Healthcare)Veterinary Dermatology, 2009
- Further validation of a pruritus severity scale for use in dogsVeterinary Dermatology, 2009
- Therapeutic Effects of Topical Application of Ozone on Acute Cutaneous Wound HealingJournal of Korean Medical Science, 2009
- Development of an owner‐assessed scale to measure the severity of pruritus in dogsVeterinary Dermatology, 2007