A study on evaluating blood urea and serum creatinine in diabetes mellitus patients
Open Access
- 15 January 2022
- journal article
- Published by IP Innovative Publication Pvt Ltd in International Journal of Clinical Biochemistry and Research
- Vol. 8 (4), 285-288
- https://doi.org/10.18231/j.ijcbr.2021.061
Abstract
Diabetes is one of the leading causes for end stage renal disease and nephropathy. Increases of blood urea and serum creatinine are due to abnormal renal function and also reduction in glomerular filtration rate. So, Urea and Creatinine are the ideal biomarkers to correlate the progression of diabetic nephropathy. Aim of the study is to evaluate the blood urea & serum creatinine with HbA1C in Diabetes mellitus patients.: A total of 50 cases and 30 controls were selected in our study. Blood samples were collected for blood urea, serum creatinine, HbA1C, Fasting plasma glucose and Post prandial blood sugar with age limit of 35-65 years. Mean ±SD was calculated for all these parameters. Blood urea and Serum creatinine are statistically significant in Diabetic patients when compared to the controls.Our study shows that blood urea and serum creatinine can be used as biomarkers in the early detection of diabetic nephropathy. These parameters help in reducing the severity of renal failure.Keywords
This publication has 14 references indexed in Scilit:
- Type 2 Diabetes MellitusPublished by Elsevier BV ,2011
- Diabetes Mellitus and CKD Awareness: The Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES)American Journal of Kidney Diseases, 2009
- UK Renal Registry 11th Annual Report (December 2008): Chapter 14 UK Renal Registry and international comparisonsNephron Clinical Practice, 2009
- Trends in incidence of treated end‐stage renal disease, overall and by primary renal disease, in persons aged 20–64 years in Europe, Canada and the Asia‐Pacific region, 1998–2002Nephrology, 2007
- An Update on the Etiology and Epidemiology of Diabetes MellitusAnnals of the New York Academy of Sciences, 2006
- The epidemiology of chronic kidney diseaseKidney International, 2005
- QUERCETIN, AN ANTI‐OXIDANT BIOFLAVONOID, ATTENUATES DIABETIC NEPHROPATHY IN RATSClinical and Experimental Pharmacology and Physiology, 2004
- Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64)Kidney International, 2003
- Global and societal implications of the diabetes epidemicNature, 2001
- A RAPID AND PRECISE METHOD FOR THE DETERMINATION OF UREAJournal of Clinical Pathology, 1960