Problems and solutions in IGRT for cervical cancer
- 1 November 2018
- journal article
- review article
- Published by VM Media Group sp. z o.o in Reports of Practical Oncology and Radiotherapy
- Vol. 23 (6), 517-527
- https://doi.org/10.1016/j.rpor.2018.05.002
Abstract
The contribution of Image-guided Radiotherapy (IGRT) to modern radiotherapy is undeniable, being the way to bring into daily practice the dosimetric benefits of Intensity-Modulated Radiotherapy (IMRT). Organ and target motion is constant and unpredictable at the pelvis, thus posing a challenge to the safe execution of IMRT. There are potential benefits of IMRT in the radical treatment of cervical cancer patients, both in terms of dose escalation and decrease of toxicity. But it is essential to find IGRT solutions to control the aspects that can lead to geographic miss targeting or organs at risk (OAR) overdose. This review seeks to describe the problems and possible solutions in the clinical implementation of IMRT/IGRT protocols to treat intact cervical cancer patients. (c) 2018 Greater Poland Cancer Centre. Published by Elsevier Sp. z o.o. All rights reserved.Keywords
This publication has 46 references indexed in Scilit:
- Optimized Planning Target Volume for Intact Cervical CancerEndocrine, 2012
- Individualized Nonadaptive and Online-Adaptive Intensity-Modulated Radiotherapy Treatment Strategies for Cervical Cancer Patients Based on Pretreatment Acquired Variable Bladder Filling Computed Tomography ScansEndocrine, 2012
- Tumor Tracking In Cervical Cancer Patients Based On Implanted Polymeric MarkersEndocrine, 2011
- The effect of uterine motion and uterine margins on target and normal tissue doses in intensity modulated radiation therapy of cervical cancerPhysics in Medicine & Biology, 2011
- Intensity-Modulated Radiotherapy in Patients with Cervical Cancer. An intra-individual Comparison of Prone and Supine PositioningRadiation Oncology, 2010
- Pelvic Radiotherapy for Cancer of the Cervix: Is What You Plan Actually What You Deliver?Endocrine, 2009
- Cervix Regression and Motion During the Course of External Beam Chemoradiation for Cervical CancerEndocrine, 2009
- Inter- and Intrafractional Tumor and Organ Movement in Patients With Cervical Cancer Undergoing Radiotherapy: A Cinematic-MRI Point-of-Interest StudyEndocrine, 2008
- Interfractional variation of uterine position during radical RT: Weekly CT evaluationGynecologic Oncology, 2007
- Small bowel displacement system-assisted intensity-modulated radiotherapy for cervical cancerGynecologic Oncology, 2004