The Nilgai antelope is a large bovid free-ranching in 17 Indian states and 31 districts of Bihar, India. It is endemic to the Indian subcontinent and while there are major populations in northern India. The government of many Indian states have declared this mammal (Nilgai) as vermin due to damage of crops and ordered to kill them in favour of farmers. In Bihar 3228 nilgais were killed by a professional shooters during 2017-2019. However, the brutality of this elegant species (Nilgai) is not a long-term explanation to conquer the human-animal battle. All the species on the earth dispense some structure and function to an ecosystem. In the present nearby investigation was executed to commence the availability, efficacy, economic worth, structure, the functional and ecological significance of Nilgai. Additionally this study gives an idea that how to use the nilgai to coverage on long term human resolve to the conflict. Its monetary economic betterment for human in many ways only requirement to reconnoitre their conventions. Silviculture based cropping system, domestication, agricultural husbandry, nilgai ranches, tourism and recreation help manage the eco-friendly earth’s climate. Nilgai antelope may be beneficial in other ways like its by-products, pedigree of food, industry outcome, taming ranches etc. Blue bull or Nilgai meat and alternative non-cow milk may provide a source of protein for ever-creasing human population. The flesh of Nilgai is highly demanded in national as well as foreign countries. It may be exported after taming, domestication. The domestication of Nilgai corresponds to pivoted changes in history not only of human but also of the biosphere. Nilgai is powerful succeeding economic contender it may prove a driving force in upliftment of socio-economic of farmers & local humans communities and eco-friendly, sustainable development of India.