Incidence, Risk Factors, and Prognosis of Hidradenitis Suppurativa Across the Globe: Insights from the Literature
Open Access
- 1 March 2023
- journal article
- review article
- Published by Taylor & Francis Ltd in Clinical, Cosmetic and Investigational Dermatology
- Vol. ume 16, 545-552
- https://doi.org/10.2147/ccid.s402453
Abstract
Hidradenitis suppurativa, a chronic inflammatory disease of the skin, affects a patient’s quality of life to a greater extent. While the disease burden, including its incidence and prevalence, has been extensively studied in the western population, there is a paucity of data from developing countries on the epidemiology of Hidradenitis suppurativa. Therefore, a general literature review was conducted to shed light on the epidemiology of Hidradenitis suppurativa across the globe. We reviewed the most recently available information on epidemiology, including incidence, prevalence, risk factors, prognosis and quality of life, complications, and associated comorbid among patients with Hidradenitis suppurativa. The estimated global prevalence of Hidradenitis suppurativa is found to be 0.00033– 4.1%, with a relatively higher prevalence of 0.7– 1.2% in European and US populations. Both genetic and environmental factors are associated with Hidradenitis suppurativa. Patients with Hidradenitis suppurativa have associated comorbid such as cardiovascular disease, type II diabetes mellitus, mental health issues, and sleep and sexual dysfunctions. These patients spend poor quality of life and tend to be less productive. Future studies are needed to assess the burden of Hidradenitis suppurativa in developing countries. Since the disease tends to be underdiagnosed, future studies should rely on clinical diagnosis rather than self-reporting to avoid the potential of recall bias. Attention needs to be diverted to developing countries with less amount of data on Hidradenitis suppurativa.Keywords
This publication has 70 references indexed in Scilit:
- Comorbidities of hidradenitis suppurativa (acne inversa)Dermato-Endocrinology, 2010
- What causes hidradenitis suppurativa?Experimental Dermatology, 2008
- What causes hidradenitis suppurativa?Experimental Dermatology, 2008
- Three Fatal Cases of Squamous Cell Carcinoma Arising in Chronic Perineal Hidradenitis SuppurativaThe Annals of The Royal College of Surgeons of England, 2007
- Quality of life impairment in hidradenitis suppurativa: A study of 61 casesJournal of the American Academy of Dermatology, 2007
- Inversa Acne (Hidradenitis Suppurativa): A Case Report and Identification of the Locus at Chromosome 1p21.1–1q25.3Journal of Investigative Dermatology, 2006
- Cutaneous Effects of SmokingJournal of Cutaneous Medicine and Surgery, 2004
- Hidradenitis SuppurativaSouthern Medical Journal, 1998
- The prevalence of hidradenitis suppurativa and its potential precursor lesionsJournal of the American Academy of Dermatology, 1996
- A family study of hidradenitis suppurativa.Journal of Medical Genetics, 1985