Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial

Abstract

In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45-minutes of moderate intensity exercise on two occasions : 1) when using their usual insulin pump (UP) and 2) after transitioning to automated insulin delivery (AID) treatment (MiniMedTM 780G). Consensus glucose management guidelines for performing exercise were applied. Plasma glucose (PG) concentrations measured over a 3-hour monitoring period were stratified into time spent below (TBR [10.0 mmol/L]) target range. Overall, TBR (UP: 11±21 vs. AID: 3±10 %, p=0.413), TIR (UP: 53±27 vs. AID: 66±39 %, p=0.320) and TAR (UP: 37±34 vs. AID: 31±41 %, p=0.604) were similar between arms. A proportionately low number of people experienced exercise-induced hypoglycaemia (UP: n=2 vs. AID: n=1, p=1.00). In conclusion, switching to AID therapy did not alter patterns of glycaemia around sustained moderate intensity exercise in adults with T1D.