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Healthy Donor Fecal Microbiota Transplantation for Recurrent Bacterial Cholangitis in Primary Sclerosing Cholangitis – A Single Case Report

Cyriac Abby Philips, Philip Augustine, Nikhil Phadke
Journal of Clinical and Translational Hepatology , Volume 6, pp 438-441; doi:10.14218/jcth.2018.00033

Abstract: Recurrent acute bacterial cholangitis is a unique indication for liver transplantation in primary sclerosing cholangitis. We present the first report on utility of healthy donor fecal transplantation for management of recurrent acute bacterial cholangitis in a primary sclerosing cholangitis patient. We demonstrate the striking liver biochemistry, bile acid and bacterial community changes following intestinal microbiota transplantation associated with amelioration of recurrent cholangitis.
Keywords: gut microbiome / Microbiota / FMT / sclerosing cholangitis / Stool Transplant

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