We are pleased to welcome you to the 2nd Workshop on AI in Networks and Distributed Systems. This year we have expanded the scope of the workshop to include applications of Machine Learning and AI not merely in Networking, but also in Distributed Systems. The scale and complexity of today's networks and distributed systems make their design, analysis, optimization, and management a daunting task. Hence smart and scalable approaches leveraging machine learning solutions are increasingly called for to take full advantage of these systems and infrastructures.