In article the problem definition of optimization of cargo transfer process in transport hub, based on logistic conception «just in time» is offered for the first time, the constructive approach to modeling of a task is defined and are provided its original economic-mathematical models with the indication of methods of realization. The necessity is also proved for setting the task of cargo transfer process optimization at the stage of operational management of information quality factor of t regarding cargo flows and rolling stock entering the transport nodes. It is shown that this factor gives an idea of the degree of stability of the control parameters and allows us to consider the problem under the conditions of risk and in a determinate formulation.