Research Progress in the Treatment of Burn with Recombinant Human Growth Hormone
Published: 1 January 2022
Advances in Clinical Medicine , Volume 12, pp 3087-3092; https://doi.org/10.12677/acm.2022.124445
Abstract: The number of patients with severe burns is increasing. The treatment and prognosis of severe burns are very important. Severe burns can often lead to the destruction of the patient’s immune system, systemic multiple organ failure, and severe stress, inflammation, and negative nitrogen balance which can cause infection and fever on the wound. After burn, catabolism is enhanced and protein decomposition is accelerated, resulting in increased consumption of muscle, fat and other tissues of the whole body. Recombinant human growth hormone (rhGH) can regulate and increase collagen deposition on wound surface, speed up wound healing, increase nitrogen, phosphorus and potassium reserves, inhibit protein decomposition, promote protein synthesis, thus correcting negative nitrogen balance and hypoproteinemia in burn patients. It can also inhibit the inflammatory response and thereby inhibit intestinal infections.
Keywords: protein / nitrogen / treatment / stress / severe burns / wound / Hormone / Recombinant / decomposition
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