Validation of analysis method for determining ketoprofen concentration in pharmaceutical dosage form using high performance liquid chromatography
Open Access
- 31 March 2013
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 4 (1), 58-60
- https://doi.org/10.5155/eurjchem.4.1.58-60.678
Abstract
The study was conducted with the purpose to develop and validate a high performance liquid chromatography method with UV detector to determine ketoprofen content in tablet preparation using ethanol-phosphate buffer (pH = 6.0, 80:20, v:v). The method was validated toward parameters of accuracy, precision, linearity, selectivity, LOD and LOQ. The results obtained fulfill the validation requirement of the ketoprofen tablet in the form of LOD = 0.5302 ppm and LOQ = 1.7676 ppm.Keywords
This publication has 2 references indexed in Scilit:
- Method Validation in Pharmaceutical AnalysisPublished by Wiley ,2005
- Validation of HPLC Techniques for Pharmaceutical AnalysisPharmaceutical Chemistry Journal, 2004