Cyclophosphamide and varicella zoster virus induced disseminated intravascular coagulopathy with fatal outcome

Abstract

Varicella is usually a mild self-limiting disease, commonly occurring in paediatric population. However, in adults and in specific groups of patients, such as those who are immunosuppressed, varicella virus infections can be fulminant and life threatening. We are hereby reporting two cases of Pemphigus vulgaris on cyclophosphamide therapy, who succumbed due to disseminated intravascular coagulopathy (DIC) after varicella zoster virus infection.