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Multisystem Langerhans cell histiocystosis in a geriatric patient: case report

Diego M. Contreras, Grecia J. G. Gutiérrez, José M. Z. Torres, Félix O. Gutiérrez

Abstract: Langerhans cell histiocytosis is a condition of exceptional onset characterized by a proliferative event of dendritic cells with mono or multisystem involvement that predominates in the pediatric population and is identified in a smaller proportion in adults. It has a clinical impact and variable prognosis according to its location and number of organs affected. A 68-year-old male patient with clinical and immunohistochemical criteria for Langerhans cell histiocytosis with multisystem settlement with fatal outcome. It is a very rare disease, it is not exclusive to the pediatric population, with little understood pathogenesis and does not have specific treatment. In adults, the clinical impact is more aggressive, with a poorer prognosis and greater short-term complications.
Keywords: adults / multisystem / Langerhans cell / clinical impact / pediatric population / cell histiocytosis / treatment / prognosis

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