Real-World Case Studies Showing the Effective Use of Azelaic Acid in the Treatment, and During the Maintenance Phase, of Adult Female Acne Patients
Open Access
- 1 February 2023
- journal article
- research article
- Published by Taylor & Francis Ltd in Clinical, Cosmetic and Investigational Dermatology
- Vol. ume 16, 515-527
- https://doi.org/10.2147/ccid.s396023
Abstract
Acne Vulgaris is a chronic inflammatory skin disease, and one of the most prevalent inflammatory dermatoses among teenagers, affecting more than > 95% of boys and 85% of girls. Adult female acne (AFA) is a subtype of acne, pragmatically defined as affecting women over the age of 25. The clinical presentation of AFA may be distinguished from adolescent acne according to some key clinical and psychosocial characteristics. The etiopathogenic factors and the chronic clinical course that are implicated in AFA make management complex and challenging. A frequent tendency to relapse makes the requirement for maintenance therapy highly likely. Therefore, AFA typically requires a specific, tailored therapeutic approach. This paper presents six challenging case studies that demonstrate the efficacy of azelaic acid gel (AZA) in adult female acne. The six cases use AZA as monotherapy, as part of a combination regimen at treatment initiation, or as maintenance treatment (which is frequently required in this adult population). The positive outcomes achieved in this case series demonstrate that AZA can be efficacious, result in excellent patient satisfaction in mild to moderate adult female acne, and can be effective as a maintenance therapy.Keywords
This publication has 37 references indexed in Scilit:
- Adult female acne: a new paradigmJournal of the European Academy of Dermatology and Venereology, 2013
- Hormone therapy in acneIndian Journal of Dermatology, Venereology and Leprology, 2013
- Epidemiology of acne vulgarisBritish Journal of Dermatology, 2012
- European Evidence‐based (S3) Guidelines for the Treatment of AcneJournal of the European Academy of Dermatology and Venereology, 2012
- Antibiotika, Azelainsäure und Benzoylperoxid in der topische AknetherapieJDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2010
- Hormonal therapy for acne: why not as first line therapy? facts and controversiesClinics in Dermatology, 2010
- Acné de la femme de plus de 25 ans : spécifique par sa clinique et les facteurs favorisants: Étude rétrospective de 79 femmesLa Presse Médicale, 2008
- Acne: more than skin deepPublished by Oxford University Press (OUP) ,2006
- Persistent Acne in WomenAmerican Journal of Clinical Dermatology, 2006
- Stratum corneum lipids: the effect of ageing and the seasonsArchiv für dermatologische Forschung, 1996