Risk Factors for Recurrent Tracheoesophageal Fistula After Gross Type C Esophageal Atresia Repair
Open Access
- 13 May 2021
- journal article
- research article
- Published by Frontiers Media SA in Frontiers in Pediatrics
Abstract
Background: To determine the possible risk factors of recurrent tracheoesophageal fistula (rTEF) after Gross type C esophageal atresia (EA) and tracheoesophageal fistula (TEF) repair. Methods: The medical records of 343 pediatric patients with Gross type C EA/TEF who underwent surgical repair were retrospectively analyzed. The patients were retrospectively divided into two groups according to whether they had rTEF. Univariate and multivariable logistic regression analysis were performed to identify risk factors for rTEF. Results: After the diagnosis of EA/TEF, 343 patients (221 boys) underwent primary repairs after birth. According to the follow-up results (257 patients survived, 42 died, and 43 were lost to follow-up), 259 patients (257 survived and two died after rTEF repair) were included in the analysis. rTEF occurred in 33 patients (33/259, 12.74%), with a median onset time to recurrence of 3.8 (2.2, 8.2) months. Multivariate analysis showed that closing the original TEF with ligation and hospital stay ≥ 28.5 days were significant risk factors of rTEF with OR of 4.083 (1.481, 11.261) and 3.228 (1.431, 7.282). Conclusions: Surgical closure technique of original TEF and the length of initial stay could influence the occurrence of rTEF after Gross type C EA/TEF repair.This publication has 15 references indexed in Scilit:
- Thoracoscopic surgery for recurrent tracheoesophageal fistula after esophageal atresia repairDiseases of the Esophagus, 2020
- Oesophageal atresiaNature Reviews Disease Primers, 2019
- Factors Associated with Recurrence of Tracheoesophageal Fistula2018
- Management of recurrent tracheoesophageal fistula after esophageal atresia and follow-upDiseases of the Esophagus, 2017
- Long-term esophageal and respiratory outcomes in children with esophageal atresia and tracheoesophageal fistulaGastroenterology Report, 2015
- Management of Recurrent Tracheoesophageal Fistulas: A Systematic ReviewEuropean Journal of Pediatric Surgery, 2014
- Recurrent Tracheoesophageal FistulaEuropean Journal of Pediatric Surgery, 2013
- Diagnosis and surgical management of recurrent tracheoesophageal fistulasDiseases of the Esophagus, 2013
- Recurrent Tracheoesophageal Fistula and Respiratory Failure: The Role of Early Airway Endoscopic ApproachEuropean Journal of Pediatric Surgery, 2012
- The diagnosis and management of recurrent tracheoesophageal fistulasJournal of Pediatric Surgery, 2010