Refine Search

New Search

Advanced search

Results: 1

(searched for: "10.5155/eurjchem.3.3.356-358.621")
Page of 1
Articles per Page
by
Show export options
  Select all

Ali El‐Shekeil, Abeer Omer Obeid, Sama Al-Aghbari
European Journal of Chemistry, Volume 3, pp 356-358; doi:10.5155/eurjchem.3.3.356-358.621

Abstract: New benzimidazole derivatives, namely, (N-(4-methoxyphenyl)methylene]-1H-benzimidazol-2-amine (2a), (N-(3,4-dimethoxyphenyl)methylene]-1H-benzimidazol-2-amine (2b), and (N-(3,4,5-trimethoxyphenyl)methylene]-1H-benzimidazol-2-amine (2c) were synthesized by reaction of a Schiff base with malononitrile in absolute ethanol. Structures of compounds have been confirmed by IR, 1H NMR and elemental analysis. Compounds 2a-c were screened for their in vitro anticancer potential using HeLa and PC3 cells. All compounds showed limited cytotoxicity except compound 2a that showed a moderate cytotoxic effect towards HeLa cells.
Page of 1
Articles per Page
by
Show export options
  Select all