(searched for: "10.5155/eurjchem.3.3.279-282.630")
European Journal of Chemistry, Volume 3, pp 279-282; doi:10.5155/eurjchem.3.3.279-282.630
Abstract: An efficient and green condensation reaction is developed for the synthesis of (E)-arylidene-1,3-dihydroindole-2-ones; (1), using heterogeneous nanoporous acid catalyst of SBA-Pr-SO3H with pore size, 6 nm in solvent free condition. Arylidene-1,3-dihydroindole-2-ones have many pharmaceutical properties such as Tyrosin kinase inhibiton. This method has the advantages of short reaction time, isolation ease of the products, excellent yields and recyclable catalyst.